Director/PDMR Shareholding

GlaxoSmithKline PLC
11 July 2005





   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons





The Administrators of the GlaxoSmithKline Executive Supplemental Savings Plan
notified the Company and the under-mentioned persons on 8 July 2005 of changes
in their interests in Ordinary Share ADRs arising from an increase in their
interests under the Annual Investment Plan feature following the re-investment
of the dividend paid to shareholders on 7 July 2005 at a price of $48.22 per
share:-




Dr J P Garnier                                                  299.752

Dr T Yamada                                                     192.874

Mr W Calhoun                                                    308.967

Mr D Stout                                                      245.931

Mr J Ziegler                                                    79.227





This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).





S M Bicknell

Company Secretary



11 July 2005










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