Director/PDMR Shareholding

GlaxoSmithKline PLC
13 March 2006



   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares of GlaxoSmithKline plc.


7 March 2006       The Administrators of the SmithKline Beecham Employee 
                   Benefit Trust ("the Trust") notified the Company on 
                   13 March 2006 that 2,618 Ordinary shares in the Company 
                   had been sold on 7 March 2006 on behalf of participants 
                   in the SmithKline Beecham Bonus Investment Plan at a 
                   price of £14.94.

                   The Trust also notified the Company on 13 March 2006 that 
                   4,549 Ordinary shares had been transferred from the Trust 
                   to a participant in the SmithKline Beecham Bonus 
                   Investment Plan.


The Trust is a discretionary fund of which all non US employees or former
employees of GlaxoSmithKline plc and its subsidiaries are potential
beneficiaries. One of the Company's directors, Mr J Heslop is therefore
interested in the shares held in the fund from time to time in the same way as
other non US employees or former employees of GlaxoSmithKline plc and its
subsidiaries.

This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(b).



S M Bicknell
Company Secretary


13 March 2006


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