Director/PDMR Shareholding

GlaxoSmithKline PLC
18 July 2006


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons

The Administrators of the GlaxoSmithKline Annual Investment Plan notified the
Company and the under mentioned persons on 18 July 2006 of an increase in their
interests in Ordinary Shares at a price of £15.15 per share following the
re-investment of the dividend paid to shareholders on 6 July 2006:-

Dr M M Slaoui                                          150
Mr R Bondy                                             194
Mr M Dunoyer                                           73
Mr D Learmouth                                         30
Dr D Pulman                                            110
Mr A Witty                                             67

This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).

S M Bicknell
Company Secretary

18 July 2006


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