Director/PDMR Shareholding

GlaxoSmithKline PLC
11 July 2006

   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons

The Administrators of the SmithKline Beecham Mid-Term Incentive Plan notified
the Company and the under-mentioned persons on 11 July 2006 of an increase in
their interests in Ordinary Share ADRs at a price of $56.46 per ADR following
the re-investment of the dividend paid to shareholders on 6 July 2006.

Dr JP Garnier                                                      1,192.308
Dr F Calhoun                                                       121.865
Mr D Phelan                                                        229.960
Mr D Stout                                                         91.916

This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).

S M Bicknell
Company Secretary

11 July 2006


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