Director/PDMR Shareholding

GlaxoSmithKline PLC
11 July 2006


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons

The Administrators of the GlaxoSmithKline Performance Share Plan notified the
Company and the under-mentioned persons on 11 July 2006 of an increase in their
interests in Ordinary Share ADRs at a price of $56.46 per ADR following the
re-investment of the dividend paid to shareholders on 6 July 2006.

Dr JP Garnier                                                      503.336
Dr F Calhoun                                                       37.071
Mr D Phelan                                                        107.857
Mr D Stout                                                         52.234


This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).

S M Bicknell
Company Secretary

11 July 2006


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