Director/PDMR Shareholding

GlaxoSmithKline PLC
26 February 2007





   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons





I give below details of changes in interests in respect of the under-mentioned
Person Discharging Managerial Responsibility:-




Dr R G Greig                  Following the vesting of 4,509.44 Ordinary Share ADRs under the
                              GlaxoSmithKline Deferred Investment Award on 1 February 2007, Dr R G Greig
                              received a payment equivalent to £54.92 per ADR on 23 February 2007.



                              The Company was advised of this transaction on 23 February 2007.



These notifications are in accordance with Disclosure Rule 3.1.4R(1)(a).



S M Bicknell

Company Secretary



26 February 2007


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