Director/PDMR Shareholding

GlaxoSmithKline PLC
23 February 2007

Notification of Transactions of Directors, Persons Discharging Managerial
Responsibility or Connected Persons

        Completion of Performance Period ended on 31st December 2006
 in respect of awards made under the GlaxoSmithKline Performance Share Plan

The three-year performance period for the GlaxoSmithKline Performance Share Plan
(PSP) awards made in 2003, which commenced on 1 January 2004, came to an end on
31 December 2006.

The Remuneration Committee of the Board of GlaxoSmithKline plc (GSK) considered
the performance achieved in respect of the PSP awards and determined that:

•         the PSP awards made in 2003 would not vest for the Executive Directors
and Corporate Executive Team (CET) members who received these awards because the
Company's relative Total Shareholder Return (TSR) performance was below the
median;

•         the PSP awards made in 2003 to other senior executives, who have since
been appointed an Executive Director or CET member, were dependent in part on
TSR performance and in part on EPS performance. Half this award lapsed as GSK's
TSR performance was below the median and half this award vested as GSK's EPS
performance exceeded the target level for full vesting;

The following PSP awards, made in 2003, to the then Executive Directors and CET
members, who are all persons discharging managerial responsibility (PDMRs), have
not vested and have therefore lapsed.


Awards that have not vested and therefore lapsed               Ordinary Shares                ADSs

Dr JP Garnier*                                                                              200,000
Mr D Stout                                                                                   74,000
Mr R Bondy                                                          77,000
Mr D Phelan                                                                                  38,500
Mr C Viehbacher                                                                              38,500
Dr R Greig                                                                                   25,000
Mr D Pulman                                                         50,000
Mr A Witty                                                          59,000
Mr M Dunoyer                                                        29,000

* Denotes an Executive Director.

Half of the PSP awards, made in 2003, to senior executives who have since been
appointed Executive Directors or CET members, vested on 23 February 2007 and
half of the awards lapsed, as set out in the table below.

                                   Initial award of                  Final award with 50% vesting of
                                      Shares/ADSs                              Shares/ADSs
                              Shares               ADSs                Shares                ADSs
Dr M Slaoui*                   5,000                                   2,500
Mr J Heslop*                   5,000                                   2,500
Mr J Clarke                   14,000                                   7,000
Mr D Learmouth                 3,000                                   1,500
Mr W Louv                                          2,000                                    1,000

* Denotes an Executive Director

The Company, the Executive Directors and other PDMRs were informed of the
vesting on 23 February 2007.

S M Bicknell
Company Secretary

23 February 2007

Enquiries:

UK Media enquiries:                                    Philip Thomson            [phone]
                                                       Alice Hunt                [phone]
                                                       Gwenan White              [phone]

US Media enquiries:                                    Nancy Pekarek             [phone]
                                                       Mary Anne Rhyne           [phone]
                                                       Patricia Seif             (215)  751 7709

European Analyst/Investor enquiries:                   Anita Kidgell             [phone]
                                                       David Mawdsley            [phone]
                                                       Sally Ferguson            [phone]

US Analyst/ Investor enquiries:                        Frank Murdolo             [phone]
                                                       Tom Curry                 [phone]






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