Director/PDMR Shareholding

GlaxoSmithKline PLC
20 February 2007





   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons



I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares of GlaxoSmithKline plc.



   13 February 2007   The Administrators of the SmithKline Beecham Employee 
                      Benefit Trust ("the Trust") notified the Company on 19 
                      February 2007 that 1,466 Ordinary shares in the Company 
                      had been sold on 13 February 2007 on behalf of
                      participants in the SmithKline Beecham Annual Investment 
                      Plan at a price of £14.65 per share.

                      The Trust also notified the Company on 19 February 2007 
                      that 2,154 Ordinary shares had been transferred from the 
                      Trust to participants in the SmithKline Beecham Annual 
                      Investment Plan.


   16 February 2007   The Trust also notified the Company on 19 February 2007 
                      that 2,212 Ordinary shares had been transferred from the 
                      Trust to participants in the SmithKline Beecham Annual 
                      Investment Plan.


The Trust is a discretionary fund of which all non US employees or former
employees of GlaxoSmithKline plc and its subsidiaries are potential
beneficiaries. One of the Company's directors, Mr J S Heslop is therefore
interested in the shares held in the fund from time to time in the same way as
other non US employees or former employees of GlaxoSmithKline plc and its
subsidiaries.


This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(b).



S M Bicknell
Company Secretary



20 February 2007


                      This information is provided by RNS
            The company news service from the London Stock Exchange             LDLBEBBB