Director/PDMR Shareholding

GlaxoSmithKline PLC
16 February 2006


The 'Director/PDMR Shareholding' announcement for GlaxoSmithKline PLC released 
today at 14:41 under RNS No 5365Y has been re-released to facilitate onward 
transmission by third party vendors.

The announcement is unchanged and is reproduced in full below.




   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


I give below details of changes in interests in the Ordinary shares of
GlaxoSmithKline plc in respect of the under-mentioned Person Discharging
Managerial Responsibility:-


Mr J Clarke     Exercise of nil-price options on 9 February 2006 over 8,103 Ordinary shares
                granted on 15 February 2002 under the SmithKline Beecham Mid-Term Incentive
                Plan ("the MTIP"), resulting from the deferral of an award made under the
                MTIP on 28 October 1998.

                Sale of 3,323 Ordinary shares at a price of £14.98 per share.


The Company was advised of these transactions on 15 February 2006.

This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(a).


S M Bicknell
Company Secretary

16 February 2006


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