Director/PDMR Shareholding

GlaxoSmithKline PLC
09 November 2006

         Notification of Transactions of Directors, Persons Discharging

                 Managerial Responsibility or Connected Persons

The Administrators of the GlaxoSmithKline Performance Share Plan notified the
Company and the under-mentioned persons on 8 November 2006 of an increase in
their notional interests in Ordinary Shares at a price of £14.34 per share and
Ordinary Share ADRs at a price of $53.80 per ADR following the notional
re-investment of the dividend paid to shareholders on 5 October 2006.




Dr JP Garnier                              3,250.32 ADRs
Mr J S Heslop                              124.74 Ordinary shares
Dr M M Slaoui                              302.60 Ordinary shares
Mr R Bondy                                 1,272.37 Ordinary shares
Dr F Calhoun                               406.29 ADRs
Mr J Clarke                                814.68 Ordinary shares
Mr M Dunoyer                               479.21 Ordinary shares
Dr R Greig                                 406.29 ADRs
Mr D Learmouth                             88.48 Ordinary shares
Mr D Phelan                                625.69 ADRs
Dr D Pulman                                418.01 Ordinary shares
                                           197.96 ADRs
Mr D Stout                                 1,202.62 ADRs
Mr C Viehbacher                            625.69 ADRs
Mr A P Witty                               1,120.82 Ordinary shares





The notional dividends accrued will be paid out in proportion to the percentage
of participants' Performance Share Plan holdings that vest following the end of
the relevant three year measurement period.



This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).



S M Bicknell

Company Secretary



9 November 2006


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