Director/PDMR Shareholding

GlaxoSmithKline PLC
09 November 2006




   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons



The Administrators of the SmithKline Beecham Mid-Term Incentive Plan notified
the Company and the under-mentioned persons on 8 November 2006 of an increase in
their interests in Ordinary Share ADRs at a price of $53.89 per ADR following
the re-investment of the dividend paid to shareholders on 5 October 2006.



Dr JP Garnier                                                      1,300.00
Dr F Calhoun                                                       132.87
Mr D Phelan                                                        250.73
Mr D Stout                                                         100.22


This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).



S M Bicknell
Company Secretary



9 November 2006


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