Director/PDMR Shareholding

GlaxoSmithKline PLC 12 June 2006 Notification of Transactions of Directors, Persons Discharging Managerial Responsibility or Connected Persons I give below details of changes in the interests of Directors, Persons Discharging Managerial Responsibility or Connected Persons in the Ordinary Shares of GlaxoSmithKline plc. 8 June 2006 Abacus Corporate Trustee Limited, as trustee of the GlaxoSmithKline (US) Trust, ("the GSK US Trust"), sold 426 ADR Shares in the Company on behalf of participants in the GlaxoSmithKline Share Value Plan at a price of $55.23 per ADR share. The GSK US Trust transferred 885 ADR Shares to participants in the GlaxoSmithKline Share Value Plan. The Company was advised of these transactions on 9 June 2006. The GSK US Trust is a grantor trust of which all employees or former employees of SmithKline Beecham Corporation and its subsidiaries are potential beneficiaries. Two of the Company's directors, Dr J-P Garnier and Dr M M Slaoui are therefore interested in the shares held in the GSK US Trust from time to time in the same way as other employees or former employees of SmithKline Beecham Corporation and its subsidiaries. This notification relates to a transaction notified in accordance with Disclosure Rule 3.1.4R(1)(b). S M Bicknell Company Secretary 12 June 2006 This information is provided by RNS The company news service from the London Stock Exchange

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GSK (GSK)
UK 100

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