Director/PDMR Shareholding

GlaxoSmithKline PLC
07 December 2007


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons



I give below details of changes in interests in the American Depositary Shares
(ADSs) of GlaxoSmithKline plc in respect of the under-mentioned Person
Discharging Managerial Responsibility:-




Mr D Stout         The exercise on 6 December 2007 of the following options 
                   granted under the GlaxoSmithKline plc Share Option Plan:


      Number of ADSs                  Grant Date                    Option Price
                                                                       (US$)
          29,416                     20 May 1998                       49.36
          95,000                   3 December 2002                     37.25
         170,000                   15 December 2003                    44.57



The sale of 294,416 ADSs on 6 December 2007 at a price of $52.66 per ADS.

The Company was advised of this transaction on 6 December 2007.

This notification is in accordance with Disclosure and Transparency Rule 3.1.4R
(1)(a).



S M Bicknell
Company Secretary



7 December 2007


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