Director/PDMR Shareholding

GlaxoSmithKline PLC
18 October 2006





   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


The Administrators of the GlaxoSmithKline Annual Investment Plan notified the
Company and the under mentioned persons on 18 October 2006 of an increase in
their interests in Ordinary Shares at a price of £14.59 per share following the
re-investment of the dividend paid to shareholders on 5 October 2006:-


  Dr M M Slaoui                                          155

  Mr R Bondy                                             203

  Mr M Dunoyer                                           75

  Mr D Learmouth                                         30

  Dr D Pulman                                            115

  Mr A Witty                                             71



This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).



S M Bicknell
Company Secretary


18 October 2006


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