Director/PDMR Shareholding

GlaxoSmithKline PLC
10 October 2006





   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons





The Administrators of the GlaxoSmithKline Executive Supplemental Savings Plan
notified the Company and the under-mentioned persons on 6 October 2006 of
changes in their interests in Ordinary Share ADRs arising from an increase in
their interests under the Annual Investment Plan feature following the
re-investment of the dividend paid to shareholders on 5 October 2006 at a price
of $53.95 per share:-




Dr J-P Garnier                                                  297.426
Dr F Calhoun                                                    306.570
Dr D Pulman                                                     16.025
Mr D Stout                                                      244.023



This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).





S M Bicknell

Company Secretary



10 October 2006


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