Director/PDMR Shareholding

GlaxoSmithKline PLC
10 October 2006



   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


I give below details of changes in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the under-mentioned persons, arising from the
purchase of Ordinary Shares on 5 October 2006 under a Single Company ISA at a
price of £14.49 per Ordinary Share:


Mr J S Heslop                                                                4
Mr A P Witty                                                                 3



The Company and the above named persons were advised of this information on 10
October 2006.



This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).





S M Bicknell

Company Secretary



10 October 2006


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