Director/PDMR Shareholding

GlaxoSmithKline PLC
06 October 2006


  Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons

I give below details of an increase in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the personal holdings of the under-mentioned
persons at a price of £14.440 per Ordinary Share, following the re-investment of
the dividend paid to shareholders on 5 October 2006.

Mr J S Heslop                                              145
Mrs P A Heslop                                             55
Mr R Bondy                                                 232
Mr D Learmouth                                             30
Dr D Pulman                                                126
Mrs C Pulman                                               13
Mr A Witty                                                 20
Mrs C Witty                                                251

The Company and the above named persons were advised of this information on 6
October 2006.

This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).

S M Bicknell
Company Secretary

6 October 2006


                      This information is provided by RNS
            The company news service from the London Stock Exchange