Director/PDMR Shareholding

GlaxoSmithKline PLC
11 May 2006



   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


I give below details of changes in interests in the American Depositary Shares
(ADSs) of GlaxoSmithKline plc in respect of the under-mentioned person:-
                    
   8 May 2006     Sale of 600 ADSs on behalf of Mrs L Greig at $57.15 per ADS.

                  The Company was advised of this transaction on 11 May 2006.


This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(a).


S M Bicknell
Company Secretary

11 May 2006


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