Director/PDMR Shareholding

GlaxoSmithKline PLC
07 October 2005

   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons

I give below details of an increase in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the personal holdings of the under-mentioned
persons at a price of £14.514 per Ordinary Share, following the re-investment of
the dividend paid to shareholders on 06 October 2005.


Mr R Bondy                                                 145

Mr J Heslop                                                110

Mrs C Witty                                                221

Mrs C Pulman                                               11

Dr D Pulman                                                58


The Company and the above named persons were advised of this information on 07
October 2005.

This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).


S M Bicknell
Company Secretary

07 October 2005


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