Director/PDMR Shareholding

GlaxoSmithKline PLC
03 October 2005



   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


I give below details of changes in the directors' interests in the Ordinary
Shares and American Depository Shares (ADSs) of GlaxoSmithKline plc.

On 1 October 2005, the following non-executive Directors were provisionally
allocated the following awards over Ordinary Shares and ADSs in the Company
under the share allocation arrangements for non-executive Directors for the
period of service from 1 July to 30 September 2005, as listed below.


Non Executive Director         Ordinary Shares        American Depository Shares
                                                               (ADS)
Sir Christopher Gent               1,738.93
Mr Lawrence Culp                                               533.93
Sir Crispin Davis                  1,043.36
Sir Deryck Maughan                                             711.91
Sir Ian Prosser                     782.52
Dr Ronaldo Schmitz                  626.01
Dr Lucy Shapiro                                                177.97
Sir Robert Wilson                   347.78


The Company and the directors were informed of these allocations on 3 October
2005.

This notification relates to transactions notified in accordance with Disclosure
Rule 3.1.4R(1)(b).


S M Bicknell
Company Secretary

3 October 2005


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