Director/PDMR Shareholding

GlaxoSmithKline PLC 27 January 2006 Notification of Transactions of Directors, Persons Discharging Managerial Responsibility or Connected Persons I give below details of changes in the interests of Directors, Persons Discharging Managerial Responsibility or Connected Persons in the Ordinary Shares of GlaxoSmithKline plc. 24 January 2006 Abacus (GSK) Trustees Limited, as trustee of the GlaxoSmithKline Employee Trust, ("the GSK Trust"), sold 784 Ordinary Shares in the Company on behalf of participants in the SmithKline Beecham Mid-Term Incentive Plan at a price of £14.34401 per share. 24 January 2006 Abacus (GSK) Trustees Limited, as trustee of the GSK Trust, transferred 1,128 Ordinary Shares in the Company to participants in the SmithKline Beecham Mid-Term Incentive Plan. 25 January 2006 Abacus (GSK) Trustees Limited, as trustee of the GSK Trust sold 1,568 Ordinary Shares in the Company on behalf of participants in the SmithKline Beecham Mid-Term Incentive Plan at a price of £14.3728 per share. 25 January 2006 Abacus (GSK) Trustees Limited, as trustee of the GSK Trust, transferred 2,256 Ordinary Shares in the Company to participants in the SmithKline Beecham Mid -Term Incentive Plan. 25 January 2006 Abacus (GSK) Trustees Limited, as trustee of the GSK Trust, transferred 4,670 Ordinary Shares in the Company to participants in the SmithKline Beecham Employee Share Option Plan 1991. The Company was advised of these transactions on 26 January 2006. The GSK Trust is a discretionary trust of which all employees or former employees of GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Three of the Company's directors, Dr J-P Garnier, Dr T Yamada and Mr J S Heslop are therefore interested in the shares held in the GSK Trust from time to time in the same way as other employees or former employees of GlaxoSmithKline plc and its subsidiaries. This notification relates to a transaction notified in accordance with Disclosure Rule 3.1.4R (1) (b). S M Bicknell Company Secretary 27 January 2006 This information is provided by RNS The company news service from the London Stock Exchange DDLFLQFBZBBE

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GSK (GSK)
UK 100

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