Director/PDMR Shareholding

GlaxoSmithKline PLC
23 January 2007






   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons



I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares of GlaxoSmithKline plc.


   19 January 2007               Abacus (GSK) Trustees Limited, as trustee of the
                                 GlaxoSmithKline Employee Trust, ("the GSK Trust"), transferred
                                 173,244 Ordinary Shares in the Company to participants in the
                                 SmithKline Beecham Employee Share Option Plan 1991.


   19 January 2007               The GSK Trust sold 646 Ordinary Shares in the Company on behalf
                                 of participants in the GlaxoSmithKline Share Value Plan at a
                                 price of £14.05 per share.


   19 January 2007               The GSK Trust transferred 2,168 Ordinary Shares in the Company
                                 to participants in the GlaxoSmithKline Share Value Plan.


   19 January 2007               The GSK Trust also received 4,500 Ordinary shares as a result
                                 of the reversal of an incorrect exercise.


   22 January 2007               The GSK Trust transferred 33,652 Ordinary Shares in the Company
                                 to participants in the SmithKline Beecham Employee Share Option
                                 Plan 1991.





The Company was advised of these transactions on 23 January 2007.



The GSK Trust is a discretionary trust of which all employees or former
employees of GlaxoSmithKline plc and its subsidiaries are potential
beneficiaries. Three of the Company's directors, Dr J-P Garnier, Dr M M Slaoui
and Mr J S Heslop are therefore interested in the shares held in the GSK Trust
from time to time in the same way as other employees or former employees of
GlaxoSmithKline plc and its subsidiaries.



This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(b).







S M Bicknell

Company Secretary



23 January 2007


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