Director/PDMR Shareholding

GlaxoSmithKline PLC
03 January 2006


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


I give below details of changes in the directors' interests in the Ordinary
Shares and American Depository Shares (ADSs) of GlaxoSmithKline plc.

On 3 January 2006, the following non-executive Directors were provisionally
allocated the following awards over Ordinary Shares and ADSs in the Company
under the share allocation arrangements for non-executive Directors for the
period of service from 1 October to 31 December 2005, as listed below.


Non Executive Director                     Ordinary Shares        American Depository Shares
                                                                             (ADS)
Sir Christopher Gent                           1,697.22
Mr Lawrence Culp                                                            894.50
Sir Crispin Davis                              1,018.33
Sir Deryck Maughan                                                          894.50
Sir Ian Prosser                                 763.75
Dr Ronaldo Schmitz                              611.00
Dr Lucy Shapiro                                                             223.62
Sir Robert Wilson                               339.44


The Company and the directors were informed of these allocations on 3 January
2006.

This notification relates to transactions notified in accordance with Disclosure
Rule 3.1.4R(1)(b).


S M Bicknell
Company Secretary

3 January 2006


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