Director/PDMR Shareholding

GlaxoSmithKline PLC
16 January 2007


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


Following a re-valuation of the cash element of the notional investment held
within the US Retirement Savings Plan ("The Plan"), which is notionally held in
GSK Ordinary Share ADRs, the Administrators of the Plan notified GlaxoSmithKline
plc and the under-mentioned persons on 15 January 2007 of an increase in the
notional allocation of Ordinary Share ADRs on 12 January 2007 at a price of
$53.75 per share:-

Dr J-P Garnier                                                         92
Dr M M Slaoui                                                          8
Mrs C Bruck Slaoui                                                     2
Dr F Calhoun                                                           17
Dr R G Greig                                                           17
Mr D Phelan                                                            20
Dr D Pulman                                                            6
Mr D Stout                                                             44
Mr C Viehbacher                                                        8


This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).


S M Bicknell
Company Secretary

16 January 2007


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