Director/PDMR Shareholding

GlaxoSmithKline PLC
09 January 2007


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares of GlaxoSmithKline plc.
                         
   8 January 2007        Abacus Corporate Trustees Limited, as trustee of the
                         GlaxoSmithKline (US) Trust, ("the GSK US Trust"), 
                         sold 585 Ordinary Share ADRs in the Company on behalf 
                         of participants in the GlaxoSmithKline Share Value 
                         Plan at a price of $52.88 per ADR.

   8 January 2007        The GSK US Trust transferred 1,169 Ordinary Share 
                         ADRs in the Company to participants in the 
                         GlaxoSmithKline Share Value Plan.

The Company was advised of these transactions on 9 January 2007.

The GSK US Trust is a grantor trust of which all employees or former employees
of SmithKline Beecham Corporation and its subsidiaries are potential
beneficiaries. Two of the Company's directors, Dr J-P Garnier and Dr M M Slaoui
are therefore interested in the shares held in the GSK US Trust from time to
time in the same way as other employees or former employees of SmithKline
Beecham Corporation and its subsidiaries.

This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(b).


S M Bicknell
Company Secretary

9 January 2007


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