Director/PDMR Shareholding

GlaxoSmithKline PLC
05 January 2007


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


I give below details of changes in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the under-mentioned persons, arising from the
purchase of Ordinary Shares on 4 January 2007 under a Single Company ISA at a
price of £13.97 per Ordinary Share:

Mr J S Heslop                                                                5

Mr A P Witty                                                                 4


The Company and the above named persons were advised of this information on 5
January 2007.

This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).


S M Bicknell
Company Secretary

5 January 2007


                      This information is provided by RNS
            The company news service from the London Stock Exchange