Director/PDMR Shareholding

GlaxoSmithKline PLC
12 April 2006





   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons



The Administrators of the SmithKline Beecham Mid-Term Incentive Plan notified
the Company and the under-mentioned persons on 11 April 2006 of an increase in
their interests in Ordinary Share ADRs at a price of $51.88 per ADR following
the re-investment of the dividend paid to shareholders on 6 April 2006.


Dr F Calhoun                                               162.891

Dr J P Garnier                                             1,593.691

Mr D Phelan                                                307.374

Mr D Stout                                                 122.859



This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).




S M Bicknell
Company Secretary



12 April 2006








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