Director/PDMR Shareholding

GlaxoSmithKline PLC
03 January 2007




   Notification of Transactions of Directors, Persons Discharging Managerial
                     Responsibility or Connected Persons



I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares of GlaxoSmithKline plc.


   2 January 2007     Abacus (GSK) Trustees Limited, as trustee of 
                      the GlaxoSmithKline Employee Trust, ("the GSK Trust"), 
                      transferred 7,500 Ordinary Shares in the Company to 
                      participants in the SmithKline Beecham Employee Share 
                      Option Plan 1991.


The Company was advised of these transactions on 3 January 2007.

The GSK Trust is a discretionary trust of which all employees or former
employees of GlaxoSmithKline plc and its subsidiaries are potential
beneficiaries. Three of the Company's directors, Dr J-P Garnier, Dr M M Slaoui
and Mr J S Heslop are therefore interested in the shares held in the GSK Trust
from time to time in the same way as other employees or former employees of
GlaxoSmithKline plc and its subsidiaries.

This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(b).




S M Bicknell
Company Secretary

3 January 2007





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