Director/PDMR Shareholding

GlaxoSmithKline PLC
29 August 2006




   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons



Following a re-valuation of the cash element of the notional investment held
within the US Retirement Savings Plan ("The Plan"), which is notionally held in
GSK Ordinary Share ADRs, the Administrators of the Plan notified GlaxoSmithKline
plc and the under-mentioned persons on 29 August 2006 of an increase in the
notional allocation of Ordinary Share ADRs on 25 August 2006 at a price of
$54.55 per share:-


Dr M M Slaoui                                                          8
Dr R Greig                                                             3



This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).



S M Bicknell

Company Secretary

29 August 2006


                      This information is provided by RNS
            The company news service from the London Stock Exchange