Director/PDMR Shareholding

GlaxoSmithKline PLC
10 April 2006



   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


I give below details of changes in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the under-mentioned person, arising from the
purchase of Ordinary Shares on 6 April 2006 under a Single Company ISA at a
price of £14.99 per Ordinary Share:


Mr J Heslop                 5


The Company and the above named person were advised of this information on 7
April 2006.

This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(b).


S M Bicknell
Company Secretary

10 April 2006



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