Director/PDMR Shareholding

GlaxoSmithKline PLC
10 April 2006



   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares of GlaxoSmithKline plc in respect of the under-mentioned person(s)
arising from the purchase of Ordinary Shares at a price of £14.99 per Ordinary
Share on 6 April 2006 through the Company's ShareReward Plan ("the Plan") which
the under-mentioned persons entered on 5 October 2001:
                         
Mr J S Heslop            Acquisition of 9 Ordinary Shares under the Dividend 
                         Reinvestment element of the Plan

Mr R Bondy               Acquisition of 9 Ordinary Shares under the Dividend 
                         Reinvestment element of the Plan

Dr D Pulman              Acquisition of 7 Ordinary Shares under the Dividend 
                         Reinvestment element of the Plan

Mr C Viehbacher          Acquisition of 3 Ordinary Shares under the Dividend 
                         Reinvestment element of the Plan

Mr A P Witty             Acquisition of 9 Ordinary Shares under the Dividend 
                         Reinvestment element of the Plan

Mrs J V Younger          Acquisition of 9 Ordinary Shares under the Dividend 
                         Reinvestment element of the Plan


The Company and the above-mentioned persons were advised of this information on
7 April 2006.

This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).


S M Bicknell
Company Secretary

10 April  2006




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