Director/PDMR Shareholding

GlaxoSmithKline PLC
02 April 2007









   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons



I give below details of changes in interests in the Ordinary shares of
GlaxoSmithKline plc in respect of the under-mentioned Person Discharging
Managerial Responsibility:-


Mr A Witty                    Sale of 6,000 Ordinary Shares on 30 March 2007 at a price of £13.93 per
                              share.



The Company was advised of this transaction on 2 April 2007.



This notification is in accordance with Disclosure Rule 3.1.4R(1)(a).



S M Bicknell

Company Secretary



2 April 2007


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