Director Declaration

GlaxoSmithKline PLC
26 February 2001



                             Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

22       Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome
February Employee Trust ('the Trust'), transferred 16,059 Ordinary Shares in
2001     the Company to participants of the Glaxo Wellcome International Share
         Option Scheme and the Glaxo Wellcome 1999 Share Option Plan.



The Company was advised of this transaction on 23 February 2001.


The Trust is a discretionary trust of which all employees or former employees
of Glaxo Wellcome plc and its subsidiaries are potential beneficiaries. Two of
the Company's directors, Sir Richard Sykes and John Coombe, as directors of
Glaxo Wellcome plc, are therefore interested in the shares held in the Trust
from time to time in the same way as other employees or former employees of
Glaxo Wellcome plc and its subsidiaries.



S M Bicknell

Company Secretary



26 February 2001