Holding(s) in Company

Advance Focus Fund Ltd has today received the following notification
of a major interest in its shares.

TR-1(i): NOTIFICATION OF MAJOR INTERESTS IN SHARES

1. Identity of the issuer or the underlying issuer of existing shares
to which voting rights are attached (ii):
Advance Focus Fund Ltd
GB0031991879

2. Reason for the notification (please state Yes/No): (    )

An acquisition or disposal of voting rights: (Yes)

An acquisition or disposal of financial instruments which may result
in the acquisition of shares already issued to which voting rights
are attached: (No)

An event changing the breakdown of voting rights: (No )

Other (please specify) : (No)

3. Full name of person(s) subject to the notification obligation
(iii):
UBS Global Wealth Management and Business Banking

4. Full name of shareholder(s) (if different from 3.) (iv):
UBS Wealth Management (UK) Ltd

5. Date of the transaction (and date on which the threshold is
crossed or  reached if different) (v):
22 January 2007

6. Date on which issuer notified:
24 January 2007

7. Threshold(s) that is/are crossed or reached:
5.95%

8. Notified details:
.......


A: Voting rights attached to shares


Class/type of shares if possible Situation previous to the Triggering
using the ISIN CODE                        transaction (vi)
                                 Number of shares   Number of voting
                                                    Rights (viii)
GB0031991879                     First time
                                 disclosure



Resulting situation after the triggering transaction (vii)


Class/type of shares if    Number of Number of voting % of voting
possible using the ISIN    shares    rights (ix)      rights
CODE
                           Direct    Direct Indirect  Direct Indirect
                                     (x)    (xi)
GB0031991879               1,495,000        1,495,000        5.95%


B: Financial Instruments
Resulting situation after the triggering transaction (xii)


Type of    Expiration  Exercise/Conversion Number of voting    % of
financial  Date (xiii) Period/ Date (xiv)  rights that may be  voting
instrument                                 acquired if the     rights
                                           instrument is
                                           exercised/
                                           converted.
-          -           -                   -                   -



Total (A+B)

Number of voting rights % of voting rights
1,495,000               5.95%


9. Chain of controlled undertakings through which the voting rights
and/or the financial instruments are effectively held, if applicable
(xv):
UBS Wealth Management (UK) Ltd - 1,495,000 - 5.95%

Proxy Voting:

10. Name of the proxy holder:
UBS Wealth Management (UK) Ltd on behalf of a number of Wealth
Management clients.

11. Number of voting rights proxy holder will cease to hold:
-

12. Date on which proxy holder will cease to hold voting rights:
-
13. Additional information:
.......

14. Contact name:
Angela Huff
Associate Director
UBS AG

15. Contact telephone number:
0207 568 4981



The person making this annoucement on behalf of Advance Focus Fund
Ltd is as follows;

Anthony Lee - tel [phone]

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