Research Update

Deltex Medical Group PLC 24 September 2004 Deltex Medical Group plc Further confirmation of CardioQ's benefits 30% reduction in hospital stay and the potential to save NHS £1 billion a year 24 September 2004: Deltex Medical Group plc ('Deltex' or the 'Company'), the haemodynamic monitoring company, today announces the results of a randomised controlled clinical trial conducted at Worthing Hospital investigating the impact of haemodynamic optimisation, using the Company's CardioQ system, on patients undergoing bowel surgery. The clinical trial results, presented by Worthing Hospital's consultant anaesthetist Dr Howard Wakeling at the annual Association of Anaesthetists of Great Britain and Ireland conference in Cardiff, showed that use of the CardioQ system significantly reduced post-surgical complications, improved patient outcomes and saved approximately £25,000 across the 64 patients who were treated with the device. The trial demonstrated that giving fluid to patients based on blood flow measurements using the CardioQ system significantly improved patient outcomes compared to the current best (though far from routine) practice of patient management based on blood pressure measurements. This result complements recent studies completed 'in the field' by anaesthetists and surgeons at the Medway Maritime Hospital NHS Trust in Gillingham, Kent. Working with senior hospital managers, consultant anaesthetist Dr Graeme Sanders and team analysed the impact of routinely using the CardioQ system across a range of moderate and major surgical procedures. Further data has now been collected and its analysis completed, which demonstrates that across the whole audit the average length of a hospital stay was reduced by 30%, compared to the 20% announced previously. Medway Maritime Hospital NHS Trust Chief Executive, Andy Horne, commented: 'We have used the CardioQ in around 200 operations in the last four months and have had very good results. It has improved quality of care for patients as they are healthier post-theatre, need less post-operative care and get home quicker. In addition to improving patient outcomes it improves efficiency and saves the Trust a considerable amount of money. We are able to treat more patients because they stay in hospital for shorter times. It is a win, win situation. CardioQ could potentially save the Medway Maritime Hospital Trust at least £1 million a year, which is equivalent to the running costs of one ward for a year. ' Deltex Chief Executive, Andy Hill, commented: 'The clinical trials undertaken at Worthing further highlight the clinical and economic benefits of haemodynamic optimisation in patients undergoing surgery. If every major surgery hospital in the UK adopted hameodynamic optimisation as standard during/post operative care, we estimate that it could potentially save the NHS around £1billion a year. The benefits of the CardioQ system have been demonstrated scientifically and in the real world of the hospital - we believe it should be incorporated as a standard of care as a matter of urgency.' For further information, please contact:- Deltex Medical Group plc Nigel Keen, Chairman 01243 774 837 Andy Hill, Chief Executive Ewan Phillips, Finance Director Financial Dynamics Lucy Briggs 020 7269 7223 David Yates 020 7269 7156 Notes for Editors Deltex Medical manufactures and markets the CardioQ monitor, which uses disposable ultra-sound probes inserted into the oesophagus to determine the amount of blood being pumped around the body - 'circulating blood volume'. Reduced circulating blood volume is known as hypovolemia, which leads to insufficient oxygen being delivered to the organs. This causes medical complications including peripheral and major organ failure which can lead to death. Hypovolemia, which is akin to severe dehydration, affects virtually every patient having surgery because of the combined effects of pre-operative starvation, the impact of the anaesthetic agents and trauma from the surgery itself. Using fluids and drugs, guided by the CardioQ, to optimise the amount of circulating blood significantly reduces post-operative complications allowing patients to make a faster, more complete recovery and return home earlier. The CardioQ incorporates the Company's proprietary software and a small diameter, easy-to-use, minimally invasive, disposable oesophageal probe that is used for transmitting and receiving an ultra-sound signal. By using this technology, the CardioQ provides clinicians with the ability to haemodynamically optimise critically ill patients and those undergoing routine moderate to major surgery through the controlled administration of fluid and drugs. Haemodynamic optimisation has been scientifically proven to improve the speed and quality of patient recovery and reduce hospital stay. There are already over 1,250 CardioQs currently in use in hospitals worldwide and distribution arrangements are in place in over 30 countries. In addition, there are currently more than 90 clinical publications on the use of the CardioQ which have repeatedly:- • validated the results of the Monitor against known standards for measuring cardiac output, demonstrating that the technology works • proved that the CardioQ works in a wide range of surgical procedures • demonstrated that the Company's technology provides significant health and economic benefits by helping to reduce post-operative complications and length of hospital stays by an average of 30 to 40 per cent for a wide range of patients. This information is provided by RNS The company news service from the London Stock Exchange
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