Holding(s) in Company

Cambridge Antibody Tech Group PLC
10 October 2003


                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES

1) Name of company

Cambridge Antibody Technology

2) Name of shareholder having a major interest

Genzyme Corporation

3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is a
holding of that person's spouse or children under the age of 18

As in 2) above


4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them

As in 2) above

5) Number of shares/amount of stock acquired

1,800,000 ordinary shares of 10 pence

6) Percentage of issued class

4.93%

7) Number of shares/amount of stock disposed

Nil

8) Percentage of issued class

N/A

9) Class of security

Ordinary 10 pence shares

10) Date of transaction

Shares issued and admitted to trading 25 September 2003

11) Date company informed

9 October 2003

12) Total holding following this notification

2,107,982


13) Total percentage holding of issued class following this notification

5.5%

14) Any additional information



15) Name of contact and telephone number for queries

Justin Hoskins, 01223 474471

16) Name and signature of authorised company official responsible for
making this notification

Diane Mellett, Company Secretary

Date of notification 10 October 2003

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