Holding(s) in Company

Cambridge Antibody Tech Group PLC
24 October 2003

                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES


1)   Name of company
Cambridge Antibody Technology


2)   Name of shareholder having a major interest
Morgan Stanley Securities Limited


3)   Please state whether notification indicates that it is in respect of
     holding of the shareholder named in 2 above or in respect of a
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18
Non Beneficial


4)   Name of the registered holder(s) and, if more than one holder, the
     number of shares held by each of them

Not known



5)   Number of shares/amount of stock acquired
Not known


6)   Percentage of issued class
Not known


7)   Number of shares/amount of stock disposed
Nil


8)   Percentage of issued class
Nil


9)   Class of security
Ordinary 10 pence shares


10)  Date of transaction
21 October 2003


11)  Date company informed
24 October 2003


12)  Total holding following this notification
1,417,152


13)  Total percentage holding of issued class following this notification
3.70%


14)  Any additional information


15)  Name of contact and telephone number for queries
Diane Mellett 01223 471471


16)  Name and signature of authorised company official responsible for
     making this notification


Diane Mellett Company Secretary


     Date of notification 24 October 2003




                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES


1)   Name of company
Cambridge Antibody Technology


2)   Name of shareholder having a major interest
Genzyme Corporation


3)   Please state whether notification indicates that it is in respect of
     holding of the shareholder named in 2 above or in respect of a
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18
As in 2 above


4)   Name of the registered holder(s) and, if more than one holder, the
     number of shares held by each of them
As in 2 above


5)   Number of shares/amount of stock acquired
2,500,000


6)   Percentage of issued class
6.52%


7)   Number of shares/amount of stock disposed
Nil


8)   Percentage of issued class
Nil


9)   Class of security
Ordinary 10 pence shares


10)  Date of transaction
Shares issued and admitted to trading 20 October 2003


11)  Date company informed
24 October 2003


12)  Total holding following this notification
4,607,982


13)  Total percentage holding of issued class following this notification
11.28%


14)  Any additional information


15)  Name of contact and telephone number for queries
Diane Mellett, 01223 471471


16)  Name and signature of authorised company official responsible for
     making this notification



Diane Mellett, Company Secretary

     Date of notification 24 October 2003





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