Holding in Company

Cambridge Antibody Tech Group PLC
26 September 2001


                                 SCHEDULE 10

                  NOTIFICATION OF MAJOR INTERESTS IN SHARES

1) Name of company
Cambridge Antibody Technology


2) Name of shareholder having a major interest
Janus Capital Corporation


3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is a
holding of that person's spouse or children under the age of 18
Funds held on behalf of clients and funds managed


4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them
Not disclosed


5) Number of shares/amount of stock acquired
Nil


6) Percentage of issued class
Nil


7) Number of shares/amount of stock disposed
506,000


8) Percentage of issued class
1.43%


9) Class of security
Ordinary 10p share


10) Date of transaction
Unknown


11) Date company informed
25 September 2001


12) Total holding following this notification
864,752



13) Total percentage holding of issued class following this notification
2.44%


14) Any additional information
None


15) Name of contact and telephone number for queries
Diane Mellett, 01763 263233


16) Name and signature of authorised company official responsible for
making this notification
Diane Mellett, Company Secretary


Date of notification 26 September 2001