Holding by Fleming Mercantile

Cambridge Antibody Technology Group PLC
7 December 1999


Schedule 10 - Notification of Major Interests in Shares

1   Name of company:
Cambridge Antibody Technology

2   Name of shareholder having a major interest:
The Fleming Mercantile Investment Trust plc

3   Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18:
As in 2

4   Name of registered holder(s) and, if more than one holder, the number of
shares held by each of them:
Robert Fleming Nominees Limited

5   Number of shares/amount of stock acquired:
221,000

6   Percentage of issued class:
0.87%

7   Number of shares/amount of stock disposed:


8   Percentage of issued class:


9   Class of security:
10p ordinary shares

10  Date of transaction:
Unknown

11  Date company informed:
7 December 1999

12  Total holding following this notification:
1,021,000

13  Total percentage holding of issued class following this notification:
4.02%

14  Contact name for queries:
Diane Mellett

15 Contact telephone number:
01763 263233

16  Name of company official responsible for making notification:
Diane Mellett, Company Secretary

17  Date of notification:
7 December 1999