Director Shareholding

Cambridge Antibody Tech Group PLC
16 March 2005

                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS


1)  Name of company

Cambridge Antibody Technology Group plc


2)  Name of director

Sir Aaron Klug


3)  Please state whether notification indicates that it is in respect of
    holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is a
holding of that person's spouse or children under the age of 18 or in respect of
a non-beneficial interest

As in 2 above


4)  Name of the registered holder(s) and, if more than one holder, the
    number of shares held by each of them (if notified)

As in 2 above


5)  Please state whether notification relates to a person(s) connected
    with the Director named in 2 above and identify the connected person(s)

As in 2 above


6)  Please state the nature of the transaction. For PEP transactions
    please indicate whether general/single co PEP and if discretionary/non
    discretionary

Sale of shares


7)  Number of shares/amount of
    stock acquired

Nil


8)  Percentage of issued class

Nil


9)  Number of shares/amount
    of stock disposed

3,587


10) Percentage of issued class

0.007%


11) Class of security

Ordinary 10 pence shares


12) Price per share

£7.10


13) Date of transaction

16 March 2005


14) Date company informed

16 March 2005


15) Total holding following this notification

27,927


16) Total percentage holding of issued class following this notification

0.054%


If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
    is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
    following this notification



23) Any additional information



24) Name of contact and telephone number for queries
Justin Hoskins
01223 898589

25) Name and signature of authorised company official responsible for
    making this notification

Diane Mellett

Date of Notification 16 March 2005


                      This information is provided by RNS
            The company news service from the London Stock Exchange