Director Shareholding-Amend

Cambridge Antibody Tech Group PLC
07 March 2005



The following replaces the previous shareholding announcement released today at
14.45 p.m. under RNS Reference 4185J.  The figures set out in the Schedule 11
Announcement for John Aston at numbers 15 and 16 are revised.


                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS


1)  Name of company
Cambridge Antibody Technology

2)  Name of director
Peter Chambre

3)  Please state whether notification indicates that it is in respect of
    holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is a
holding of that person's spouse or children under the age of 18 or in respect of
a non-beneficial interest
As in 2 Above

4)  Name of the registered holder(s) and, if more than one holder, the
    number of shares held by each of them (if notified)
As in 2 above

5)  Please state whether notification relates to a person(s) connected
    with the Director named in 2 above and identify the connected person(s)
As in 2 above

6)  Please state the nature of the transaction. For PEP transactions
    please indicate whether general/single co PEP and if discretionary/non
    discretionary
Market purchase of 3,541 shares to be held as "Invested Shares" under
Executive Incentive Plan

7)  Number of shares/amount of
    stock acquired
3,541

8)  Percentage of issued class
0.007%

9)  Number of shares/amount
    of stock disposed
None

10) Percentage of issued class
None

11) Class of security
Ordinary 10 pence shares

12) Price per share

£7.06

13) Date of transaction
4 March 2005

14) Date company informed
4 March 2005

15) Total holding following this notification
26,090

16) Total percentage holding of issued class following this notification
0.05%

If a director has been granted options by the company please complete the
following boxes

17) Date of grant
4 March 2005

18) Period during which or date on which exercisable
4 March 2008 to 3 March 2011

19) Total amount paid (if any) for grant of the option
Nil

20) Description of shares or debentures involved: class, number
10,623 Ordinary 10 pence shares

21) Exercise price (if fixed at time of grant) or indication that price
    is to be fixed at time of exercise
10 pence per share subject to Award

22) Total number of shares or debentures over which options held
    following this notification
343,566 of which:
206,974 are Options under Company Share Option Plan
 92,510 are Restricted Share Awards under Executive Incentive Plan
 44,082 are Matching Shares under Executive Incentive Plan

23) Any additional information
Awards granted under the Executive Incentive Plan are subject to performance
conditions

24) Name of contact and telephone number for queries
Justin Hoskins: 01223 898589

25) Name and signature of authorised company official responsible for
    making this notification
Diane Mellett
Date of Notification 7 March 2005


                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS


1)  Name of company
Cambridge Antibody Technology

2)  Name of director
Diane Mellett

3)  Please state whether notification indicates that it is in respect of
    holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is a
holding of that person's spouse or children under the age of 18 or in respect of
a non-beneficial interest
As in 2 Above

4)  Name of the registered holder(s) and, if more than one holder, the
    number of shares held by each of them (if notified)
As in 2 above

5)  Please state whether notification relates to a person(s) connected
    with the Director named in 2 above and identify the connected person(s)
As in 2 above

6)  Please state the nature of the transaction. For PEP transactions
    please indicate whether general/single co PEP and if discretionary/non
    discretionary
Market purchase of 495 shares to be held as "Invested Shares" under
Executive Incentive Plan

7)  Number of shares/amount of
    stock acquired
495

8)  Percentage of issued class
0.001%

9)  Number of shares/amount
    of stock disposed
None

10) Percentage of issued class
None

11) Class of security
Ordinary 10 pence shares

12) Price per share

£7.06

13) Date of transaction
4 March 2005

14) Date company informed
4 March 2005

15) Total holding following this notification
15,062

16) Total percentage holding of issued class following this notification
0.029%

If a director has been granted options by the company please complete the
following boxes

17) Date of grant
4 March 2005

18) Period during which or date on which exercisable
4 March 2008 to 3 March 2011

19) Total amount paid (if any) for grant of the option
Nil

20) Description of shares or debentures involved: class, number
1,485 Ordinary 10 pence shares

21) Exercise price (if fixed at time of grant) or indication that price
    is to be fixed at time of exercise
10 pence per share subject to Award

22) Total number of shares or debentures over which options held
    following this notification
112,786 of which:
76,874 are Options under Company Share Option Plan
31,901 are Restricted Share Awards under Executive Incentive Plan
 4,011 are Matching Shares under Executive Incentive Plan

23) Any additional information
Awards granted under the Executive Incentive Plan are subject to performance
conditions

24) Name of contact and telephone number for queries
Justin Hoskins: 01223 898589

25) Name and signature of authorised company official responsible for
    making this notification
Diane Mellett
Date of Notification 7 March 2005


                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS


1)  Name of company
Cambridge Antibody Technology

2)  Name of director
John Aston

3)  Please state whether notification indicates that it is in respect of
    holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is a
holding of that person's spouse or children under the age of 18 or in respect of
a non-beneficial interest
As in 2 Above

4)  Name of the registered holder(s) and, if more than one holder, the
    number of shares held by each of them (if notified)
As in 2 above

5)  Please state whether notification relates to a person(s) connected
    with the Director named in 2 above and identify the connected person(s)
As in 2 above

6)  Please state the nature of the transaction. For PEP transactions
    please indicate whether general/single co PEP and if discretionary/non
    discretionary
Market purchase of 3,541 shares to be held as "Invested Shares" under
Executive Incentive Plan at £7.06

Exercise of options over 25,000 shares at £2.87 and 9,964 shares at £2.42 of
which 22,273 shares were sold at £7.00 and 12,691 were retained.

7)  Number of shares/amount of
    stock acquired
38,505

8)  Percentage of issued class
0.075%

9)  Number of shares/amount
    of stock disposed
22,273

10) Percentage of issued class
0.043%

11) Class of security
Ordinary 10 pence shares

12) Price per share

See 6 above

13) Date of transaction
4 March 2005

14) Date company informed
4 March 2005

15) Total holding following this notification
59,962

16) Total percentage holding of issued class following this notification
0.12%

If a director has been granted options by the company please complete the
following boxes

17) Date of grant
4 March 2005

18) Period during which or date on which exercisable
4 March 2008 to 3 March 2011

19) Total amount paid (if any) for grant of the option
Nil

20) Description of shares or debentures involved: class, number
10,623 Ordinary 10 pence shares

21) Exercise price (if fixed at time of grant) or indication that price
    is to be fixed at time of exercise
10 pence per share subject to Award

22) Total number of shares or debentures over which options held
    following this notification
125,733 of which:
51,087 are Options under Company Share Option Plan
57,765 are Restricted Share Awards under Executive Incentive Plan
16,881 are Matching Shares under Executive Incentive Plan

23) Any additional information
Awards granted under the Executive Incentive Plan are subject to performance
conditions

24) Name of contact and telephone number for queries
Justin Hoskins: 01223 898589

25) Name and signature of authorised company official responsible for
    making this notification
Diane Mellett
Date of Notification 7 March 2005

                      This information is provided by RNS
            The company news service from the London Stock Exchange