Holding(s) in Company

Clinical Computing PLC 12 October 2007 TR-1: Notifications of Major Interests in Shares 1. Identity of the issuer or the underlying issuer of existing Clinical Computing plc shares to which voting rights are attached: 2. Reason for notification (yes/no) Yes An acquisition or disposal of voting rights No An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached No An event changing the breakdown of voting rights No Other (please specify):______________ 3. Full name of person(s) subject to notification Neil Francis Jeremy Mendoza obligation: 4. Full name of shareholder(s) (if different from 3): 5. Date of transaction (and date on which the 11th October 2007 threshold is crossed or reached if different): 6. Date on which issuer notified: 11th October 2007 7. Threshold(s) that is/are crossed or reached: From 3.47% to 4.68% 8: Notified Details A: Voting rights attached to shares Class/type of Situation previous to the Resulting situation after the triggering transaction shares triggering transaction Number of Number of Number of Number of voting rights Percentage of voting If possible shares voting shares rights use ISIN code rights 1,150,000 1,150,000 1,550,000 1p Ordinary 1,550,000 4.68% GB0002063369 Direct Indirect Direct Indirect B: Financial Instruments Resulting situation after the triggering transaction Type of financial Expiration date Exercise/ conversion No. of voting rights that Percentage of instrument period/date may be acquired (if the voting rights instrument exercised/ converted) Total (A+B) Number of voting rights Percentage of voting rights 1,550,000 4.68% 9. Chain of controlled undertakings through which the voting rights and /or the financial instruments are effectively held, if applicable: n/a Proxy Voting: 10. Name of proxy holder: 11. Number of voting rights proxy holder will cease to hold: 12. Date on which proxy holder will cease to hold voting rights: 13. Additional information: 14 Contact name: Neil Francis Jeremy Mendoza 15. Contact telephone name: 07718 636295 This information is provided by RNS The company news service from the London Stock Exchange

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Calculus VCT (CLC)
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