Holding(s) in Company

Clinical Computing PLC
18 August 2003



                  DEALINGS BY SUBSTANTIAL SHAREHOLDERS


1)   NAME OF COMPANY

     CLINICAL COMPUTING PLC

2)   NAME OF SHAREHOLDER HAVING A MAJOR INTEREST

      SECOND ADVANCE VALUE REALISATION COMPANY LIMITED

3)   Please state whether notification indicates that it is in respect of 
     holding of the Shareholder named in 2 above or in respect of a 
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18

      SHAREHOLDER

4)   Name of the registered holder(s) and, if more than one holder, the 
     number of shares held by each of them.



5)   Number of shares/amount of stock acquired.



6)   ( N/A %) of issued Class

7)   Number of shares/amount of stock disposed

      250,000

8)   (1%) of issued Class

9)   Class of security

      ORDINARY 5P

10)  Date of transaction

      15 AUG 2003

11)  Date company informed

      18 AUG 2003

12)  Total holding following this notification

      2,335,000
               
13)  Total percentage holding of issued class following this notification

      9.31%

14)  Any additional information



15)  Name of contact and telephone number for queries

      JOSEPH G MARLOVITS

       020 8747 8744


16)  Name and signature of authorised company official responsible for 
     making this notification

     Date of Notification ..18 AUGUST 2003....



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