Schedule 10 Disclosure

Finsbury Life Sciences Inv Tst PLC
1 September 2000


                                  SCHEDULE 10
                   NOTIFICATION OF MAJOR INTERESTS IN SHARES


1. Name of Company                     2. Name of Shareholder having a
                                       substantial interest
Finsbury Life Sciences Investment                   
            Trust PLC                         Prudential plc
                 
3. Please state whether                4. Name of the registered
notification indicates that it is      holder(s) and, if more than one
in respect of holding of the           holder, the number of shares held
Shareholder named in 2 above or in     by each of them
respect of a non-beneficial        
interest or in the case of an      
individual holder if it is a       
holding of that person's spouse or     HSBC GIS Nominees (UK) Ltd PAC a/c
children under the age of 18       
                 
             As in 2
                 
5. Number of     6. Percentage of      7. Number of      8. Percentage of
shares/amount of issued Class          shares/amount of  issued Class
 stock acquired                        stock disposed    
                                                             
    375,000            1.2%                   N/A               N/A
                         


9. Class of security               10. Date of       11. Date company
                                   transaction       informed
Ordinary 25p                                                 
                                    30 August 2000   1 September 2000

12. Total holding following this   13. Total percentage holding of
notification                       issued class following this
                                   notification
                                   
            2,000,000                             6.6%