Holding(s) in Company

Finsbury Life Sciences Inv Tst PLC
12 April 2005

                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES



1. Name of company


Finsbury Life Sciences Investment Trust PLC



2. Name of shareholder having a major interest


Deutsche Bank AG



3. Please state whether notification indicates that it is in respect of holding
of the shareholder named in 2 above or in respect of a non-beneficial interest
or in the case of an individual holder if it is a holding of that person's
spouse or children under the age of 18


As in 2 above



4. Name of the registered holder(s) and, if more than one holder, the number of
shares held by each of them


Deutsche Bank AG



5. Number of shares / amount of stock acquired


Not disclosed



6. Percentage of issued class


-



7. Number of shares / amount of stock disposed


Not disclosed



8. Percentage of issued class


-



9. Class of security


Ordinary shares of 25p each



10. Date of transaction


12 April 2005






11. Date company informed


 12 April 2005



12. Total holding following this notification


Nil



13. Total percentage holding of issued class following this notification


Nil



14. Any additional information


-



15. Name of contact and telephone number for queries


Tracey Lago - 020 7426 6219



16. Name and signature of authorised company official responsible for making
this notification


Tracey Lago

For and on behalf of Close Finsbury Asset Management Limited



Date of notification


12 April 2005



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for loss of business or loss of profits) arising in contract, tort or otherwise
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