Holding(s) in Company

Finsbury Life Sciences Inv Tst PLC
09 November 2004

                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES



1. Name of company


Finsbury Life Sciences Investment Trust PLC



2. Name of shareholder having a major interest


Credit Suisse First Boston Nominees Limited A/C D6M5PB



3. Please state whether notification indicates that it is in respect of holding
of the shareholder named in 2 above or in respect of a non-beneficial interest
or in the case of an individual holder if it is a holding of that person's
spouse or children under the age of 18


Non-beneficial holding - custodian interest only



4. Name of the registered holder(s) and, if more than one holder, the number of
shares held by each of them


Credit Suisse First Boston Nominees Limited A/C D6M5PB



5. Number of shares / amount of stock acquired


Not disclosed



6. Percentage of issued class


-



7. Number of shares / amount of stock disposed


Not disclosed



8. Percentage of issued class


-



9. Class of security


Ordinary shares of 25p each



10. Date of transaction


5 November 2004






11. Date company informed


 9 November 2004



12. Total holding following this notification


1,940,000



13. Total percentage holding of issued class following this notification


6.45%



14. Any additional information


At the close of business on 5 November 2004, there were no persons with an interest above 3%.



CSFB Nominees limited A/C D6M5PB nor, so far as lies within their knowledge, any of the persons named in 4 above are
party to any agreement to which section 204 of the Companies Act 1985 (the 'Act') applies.



CSFB Nominees Limited A/C D6M5PB is a member of the Credit Suisse First Boston group of companies.  Those group
companies which are direct or indirect holding companies of CSFB Nominees Limited A/C D6M5PB are, under the terms of
section 203 of the Act, each interested by attribution in any shares in which CSFB Nominees Limited A/C D6M5PB is
interested.



15. Name of contact and telephone number for queries


Tracey Lago - 020 7426 6219



16. Name and signature of authorised company official responsible for making
this notification


Tracey Lago

For and on behalf of Close Finsbury Asset Management Limited



Date of notification


9 November 2004



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