Holding in Company

Finsbury Life Sciences Inv Tst PLC
25 July 2001

                                 SCHEDULE 10

                  NOTIFICATION OF MAJOR INTERESTS IN SHARES

1) Name of company

Finsbury Life Sciences Investment Trust PLC

2) Name of shareholder having a major interest

HSBC Investment Bank Plc

3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is a
holding of that person's spouse or children under the age of 18

As above

4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them

Not stated

5) Number of shares/amount of stock acquired

Not stated

6) Percentage of issued class

Not stated

7) Number of shares/amount of stock disposed

Not stated

8) Percentage of issued class

Not stated

9) Class of security

Ordinary shares of 25p each

10) Date of transaction

not stated

11) Date company informed

24 July 2001

12) Total holding following this notification

4,323,450


13) Total percentage holding of issued class following this notification

14.4%

14) Any additional information

The interest in 16,755 shares were of a kind described in S208(5) of the
Companies Act 1985


15) Name of contact and telephone number for queries

David Fallon

Close Finsbury Asset Management Limited

Secretary

Tel: [phone]

25 July 2001