Holding(s) in Company

Ardana PLC 24 May 2007 For filings with the FSA include the annex For filings with issuer exclude the annex TR-1: Notifications of Major Interests in Shares 1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached: ARDANA PLC 2. Reason for notification (please place an X inside the appropriate bracket/s): An acquisition or disposal of voting rights: (YES) An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached: ( ) An event changing the breakdown of voting rights: ( ) Other (please specify) : ( ) 3. Full name of person(s) subject to notification obligation: MVM INTERNATIONAL LIFE SCIENCES FUND NO.1 LP, UK MEDICAL VENTURED FUND NO. 1 LP, MVM EXECUTIVE LIMITED 4. Full name of shareholder(s) (if different from 3) : 5. Date of transaction (and date on which the threshold is crossed or reached if different): 22 MAY 2007 6. Date on which issuer notified: 23 MAY 2007 7. Threshold(s) that is/are crossed or reached: 7% 8. Notified Details: CROSSED PERCENTAGE INTEGER A: Voting rights attached to shares Class/type of shares Situation previous to if possible use the Triggering transaction ISIN CODE Number of shares Number of voting Rights GB00B065JS90 6,538,640 6,538,640 ARDANA PLC ORDINARY 1P Resulting situation after the triggering transaction Class/type of shares Number of shares Number of voting rights % of voting rights if possible use ISIN CODE Direct Indirect Direct Indirect GB00B065JS90 4,338,640 4,338,640 6.62% ARDANA PLC ORDINARY 1P B: Financial Instruments Resulting situation after the triggering transaction Type of Expiration date Exercise/conversion No. of voting % of voting financial period/date rights that may rights instrument be acquired (if the instrument exercised/ converted) Total (A+B) Number of voting rights % of voting rights 4,338,640 6.62% 9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable: Proxy Voting: 10. Name of proxy holder: 11. Number of voting rights proxy holder will cease to hold: 12. Date on which proxy holder will cease to hold voting rights: 13. Additional information: HUGO HARROD 14. Contact name: 020 7557 7515 15. Contact telephone number: For notes on how to complete form TR-1 please see the FSA website. This information is provided by RNS The company news service from the London Stock Exchange
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