Transaction in Own Shares

AstraZeneca PLC
22 March 2007




REPURCHASE OF SHARES IN ASTRAZENECA PLC



Further to the announcement of its irrevocable, non-discretionary share
repurchase programme for the period 5 February 2007 to 30 April 2007,
AstraZeneca PLC announced that under the terms of that programme it purchased
for cancellation 297,316 ordinary shares of AstraZeneca PLC at a price of 2850
pence per share on 21 March 2007. Upon the cancellation of these shares, the
number of shares in issue will be 1,516,836,896.




G H R Musker

Company Secretary

22 March 2007


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