Transaction in Own Shares

AstraZeneca PLC
15 December 2006

REPURCHASE OF SHARES IN ASTRAZENECA PLC





AstraZeneca PLC announced that on 14 December 2006, it purchased for
cancellation 500,000 ordinary shares of AstraZeneca PLC at a price of 2889 pence
per share. Upon the cancellation of these shares, the number of shares in issue
will be 1,531,920,702.







G H R Musker

Company Secretary

15 December 2006


                      This information is provided by RNS
            The company news service from the London Stock Exchange